They unleashed forces which ended the whole of creation and then restarted it.
They could not accept this lack of uniqueness and fought each other. They encompassed everything except each other. In the beginning of their existence, the Brothers encompassed the whole of everything. The entities are called 'Brothers', though they are also sisters, sexless, and everything in between.
Once the Multiverse was restored in its seventh iteration, he released the Brothers to serve their pre-destined roles as architects of new realities. During the final days of the Sixth Infinity, the Living Tribunal created the Brothers, consulting the Spectre in doing so.